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Expertise
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Work
Work
Sazinsky, M. H., Lippard, S. J., in Sustaining Life on Planet Earth: Metalloenzymes Mastering Dioxygen and Other Chewy Gases, Eds. P.M.H. Kroneck, M.E. Sosa Torres; Vol. 15 of Metal Ions in Life Sciences; Eds. A. Sigel, H. Sigel, R.K.O. Sigel; Springer International Publishing AG, Cham, Switzerland, 2015, Chapter 6, 205-256.
Lee, K. H., Humbarger, S., Bhanvadia, R. Sazinsky, M. H., Crane, E. J.: "Characterization of the mechanism of the NADH-dependent polysulfide reductase (Npsr) from Shewanella loihica PV-4: Formation of a productive NADH-enzyme complex and its role in the general mechanism of NADH and FAD-dependent enzymes," Biochem. Biophys. Acta. 2014, 1844, 1708-1717.
Heller, G., Zwang, T. J., Sarapata, E. A., Haber, M. A., Sazinsky, M. H., Radunskaya, A. E., Johal, M. S.: "Accounting for unintended binding events in the analysis of quartzcrystal microbalance kinetic data," Colloids and Surfaces B: Biointerfaces, 2014, 117, 425-431.
Morrison, E., Kantz, A., Gassner, G.T., Sazinsky, M. H.: "Structure and Mechanism of Styrene Monooxygenase Reductase: New Insight into the FAD-Transfer Reaction," Biochemistry, 2013, 52, 6063-6075.
Herwald, S., Liu, A.Y., Zhu, B.E., Sea, K. W., Lopez, K.M., Sazinsky, M. H., Crane, E.J.: "Structure and substrate specificity of the pyrococcal coenzyme A disulfide reductases/polysulfide reductases (CoADR/Psr): implications for S(0)-based respiration and a sulfur-dependent antioxidant system in Pyrococcus," Biochemistry, 2013, 52, 2764-2773.
Zwang, T., Gormally, M. Johal, M., Sazinsky, M. H.: "Enhanced Iron Availability by Protein Glycation may Explain Higher Infection Rates in Diabetics," Biometals, 2012, 25, 237-245.
Song, W. J, Gucinski, G., Sazinsky, M. H., Lippard, S. J.: "Tracking a Defined Route for O2-Migration in a Dioxygen-Activating Diiron Enzyme," Proc. Natl. Acad. Sci. USA, 2011, 108, 14795-800.
Platter, E., Lawson, M., Marsh, C., Sazinsky, M. H.: "Characterization of a Non-Ribosomal Peptide Synthetase-Associated Diiron Arylamine N-Oxygenase from Pseudomonas syringae pv. phaseolicola," Arch. Biochem. Biophys., 2011, 508, 39-45.
Warner, M., Lukose, V., Lee, K.-H., Lopez, K., Sazinsky, M. H., Crane III, E. J.: "Characterization of an NADH-dependent persulfide reductase from Shewanella loihica PV-4: Implications for the mechanism of sulfur respiration via FAD-dependent enzymes," Biochemistry, 2011, 50, 194-206.
Woon Ju Song, Michael S. McCormick, Rachel K. Behan, Matthew H. Sazinsky, Wei Jiang, Jeffery Lin, Carsten Krebs, Stephen J. Lippard: "Active Site Threonine Facilitates Proton Transfer During Dioxygen Activation at the Diiron Center of Toluene/o-Xylene Monooxygenase Hydroxylase," J. Am. Chem. Soc. 2010, 132, 13582-13585.
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Education
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Awards & Honors
Awards & Honors
Pomona College, Wig Distinguished Professorship Award for Excellence in Teaching: 2010
Pomona College, Camille and Henry Dreyfus Faculty Start-Up Award, 2007